Have you ever felt alone? Felt like you are doing so much, expected to do so much, but no one really cares how you feel - as long as it's done. This my friend is called weariness. Whenever the heart becomes disgruntled about something, we tend to take it out on those around us; but the truth is, we are taking it out on God. God is the one that is in control of your life. There is nothing that can happen to you unless He allows it. So even the fact that it seems as if no one is there. Even that is by the will of God.
The next question is, do you trust Him? Has He become a sinner, because your life isn't going the way you would have it go? God forbid! God cannot sin! However, our weariness is a manifestation of our selfishness. Keep your eyes on the Lord Jesus Christ, and do all things unto Him, Not with eyeservice, as menpleasers; but as the servants of Christ, doing the will of God from the heart; (Eph 6:6).
If you do what you do unto the Lord, you will recognise that He accepts your sacrifices, and He is pleased with what you offer Him. It doesn't matter if people do not appreciate what you do when God does. Do not do what you do to be esteemed in the eyes of people; do it unto the Lord, and glorify Him, by willingly submitting to His path. He loves you!